a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	DNA topoisomerase II (DNA topoisomerase II (EC 5.99.1.3) (from PhosphoBase))
Seq-ID:	P06786 [Saccharomyces cerevisiae]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process DNA topoisomerase (ATP-hydrolyzing) activity, ATP binding, protein binding synaptonemal complex, mitochondrion reciprocal meiotic recombination, DNA strand elongation involved in DNA replication, regulation of mitotic recombination, chromatin remodeling at centromere, chromatin assembly or disassembly, DNA topological change, mitotic cell cycle G2/M transition decatenation checkpoint
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	1086	AEQINDVKGATSDEEDEESSH	CK2_group	1332607	LTP	0.33	MOD_CK2_1	-	TOP4c	0.74	-	-
S	1087	EQINDVKGATSDEEDEESSHE	CK2_group	1332607	LTP	0.23	MOD_CK2_1	-	TOP4c	0.76	-	-
T	1258	EKTPSVSETKTEEEENAPSST	CK2_group	1332607	LTP	0.13	MOD_CK2_1	-	-	0.84	-	-
S	1266	TKTEEEENAPSSTSSSSIFDI	CK2_group	1332607	LTP	0.57		-	-	0.71	-	-
S	1269	EEEENAPSSTSSSSIFDIKKE	CK2_group	1332607	LTP	0.62		-	-	0.69	-	-
S	1272	ENAPSSTSSSSIFDIKKEDKD	CK2_group	1332607	LTP	0.58		-	-	0.68	-	-
S	1353	VRKQQKVVELSGESDLEILDS	CK2_group	1332607	LTP	0.23	MOD_CK2_1	-	-	0.57	-	-
S	1356	QQKVVELSGESDLEILDSYTD	CK2_group	1332607	LTP	0.10	MOD_CK2_1	-	-	0.56	-	-
S	1408	YVETLELSDDSFIEDDEEENQ	CK2_group	1332607	LTP	0.11	MOD_CK2_1	-	-	0.71	-	-
S	1423	DEEENQGSDVSFNEED	CK2_group	1332607	LTP	0.13	MOD_CK2_1	-	-	0.85	-	-

Substrate:	DNA topoisomerase II (DNA topoisomerase II (EC 5.99.1.3) (from PhosphoBase))
Seq-ID:	P15348 [Drosophila melanogaster]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process DNA topoisomerase (ATP-hydrolyzing) activity, four-way junction DNA binding, mRNA binding, rDNA binding, ATP binding, satellite DNA binding chromatin accessibility complex, cytoplasm, chromosome, insoluble fraction, soluble fraction chromatin silencing, mitotic spindle organization, DNA topological change, mitotic chromosome condensation, meiosis, metaphase plate congression
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	1284	GKQIKAEPDASGDEVDEFDAM	-	18327897	HTP	0.42		-	-	0.75	-	medium
S	1284	GKQIKAEPDASGDEVDEFDAM	-	18327897	HTP	0.42		-	-	0.75	-	medium
S	1344	IDFSKAKAKKSDDDVEEVTPR	-	18327897	HTP	0.44		-	-	0.76	-	medium
S	1344	IDFSKAKAKKSDDDVEEVTPR	-	18327897	HTP	0.44		-	-	0.76	-	medium
T	1352	KKSDDDVEEVTPRAERPGRRQ	-	18327897	HTP	0.19		-	-	0.89	-	medium
T	1352	KKSDDDVEEVTPRAERPGRRQ	-	18327897	HTP	0.19		-	-	0.89	-	medium
S	1374	SKKIDYSSLFSDEEEDGGNVG	-	18327897	HTP	0.10		-	-	0.74	-	medium
S	1374	SKKIDYSSLFSDEEEDGGNVG	-	18327897	HTP	0.10		-	-	0.74	-	medium
S	1385	DEEEDGGNVGSDDDGNASDDD	-	18327897	HTP	0.69		-	-	0.92	-	medium
S	1385	DEEEDGGNVGSDDDGNASDDD	-	18327897	HTP	0.69		-	-	0.92	-	medium
S	1392	NVGSDDDGNASDDDSPKRPAK	-	18327897	HTP	0.72		-	-	0.93	-	medium
S	1392	NVGSDDDGNASDDDSPKRPAK	-	18327897	HTP	0.72		-	-	0.93	-	medium
S	1396	DDDGNASDDDSPKRPAKRGRE	-	18327897	HTP	0.11		-	-	0.93	-	medium
S	1396	DDDGNASDDDSPKRPAKRGRE	-	18327897	HTP	0.11		-	-	0.93	-	medium